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Congenital fiber-type disproportion myopathy
2 OMIM references -
7 associated genes
8 signs/symptoms
PROTEIN INTERACTIONS: 1
Neuralgic amyotrophy
1 OMIM reference -
1 associated gene
15 signs/symptoms
Congenital fiber-type disproportion myopathy
Neuralgic amyotrophy

ACTA1
(UniProt - OMIM)
 SEPT9
(UniProt - OMIM)
ITGA7
(UniProt - OMIM)
MYL2
(UniProt - OMIM)
PTPLA
(UniProt - OMIM)
SEPN1
(UniProt - OMIM)
TPM2
(UniProt - OMIM)
TPM3
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
TPM3
(0.49)
SEPT9


Citations in the biomedical literature:


Congenital fiber-type disproportion myopathy
ACTA1 ITGA7 MYL2 PTPLA SEPN1 TPM2
TPM3
Neuralgic amyotrophy
SEPT9



Congenital fiber-type disproportion myopathy
Neuralgic amyotrophy

Synonym(s):
- CFTDM
Synonym(s):
- Acute brachial plexus neuritis
- Brachial plexus neuritis
- Immune brachial plexus neuropathy
- Mononeuritis multiplex with brachial predilection
- Neuralgic shoulder amyotrophy
- Serum neuritis
- Winged scapula
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare neurologic disease
Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Diseases of the nervous system -
Epidemiological data:
Class of prevalence: unknown
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: 6-9 / 10 000
Average age onset: adulthood
Average age of death: normal
Type of inheritance: autosomal dominant
External references:
2 OMIM references -
No MeSH references
External references:
1 OMIM reference -
No MeSH references
Congenital fiber-type disproportion myopathy
Neuralgic amyotrophy

Very frequent
- Abnormal muscle biopsy / muscle enzymes / CPK / LDH / aldolase / creatin phosphokinase
- Areflexia / hyporeflexia
- Autosomal recessive inheritance
- Hypotonia
- Myopathy

Frequent
- Pectus excavatum
- Repeat respiratory infections
- Scoliosis



Very frequent
- Abnormal EMG / electromyogram / electropmyography
- Articular / joint pain / arthralgia
- Muscle weakness / flaccidity
- Neuritis / polyneuritis / multineuritis

Frequent
- Paresthesia / dysesthesia / hypoesthesia / anesthesia / numbness
- Scapula structural / position anomaly / congenital elevation / Sprengel anomaly

Occasional
- Acrocyanosis / Raynaud's phenomenon / vasomotor disorders
- Cleft lip and palate
- Elocution disorders / dysarthria / dysphonia
- Microstomia / little mouth
- Peripheral neuropathy
- Respiratory distress / dyspnea / respiratory failure / lung volume reduction
- Round face
- Short stature / dwarfism / nanism
- Sleep and vigilance disorders